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Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CL(pro)
After the emergence of the pandemic, repurposed drugs have been considered as a quicker way of finding potential antiviral agents. SARS-CoV-2 3CL(pro) is essential for processing the viral polyproteins into mature non-structural proteins, making it an attractive target for developing antiviral agent...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064871/ https://www.ncbi.nlm.nih.gov/pubmed/33901557 http://dx.doi.org/10.1016/j.ijbiomac.2021.04.129 |