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Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CL(pro)

After the emergence of the pandemic, repurposed drugs have been considered as a quicker way of finding potential antiviral agents. SARS-CoV-2 3CL(pro) is essential for processing the viral polyproteins into mature non-structural proteins, making it an attractive target for developing antiviral agent...

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Detalles Bibliográficos
Autores principales:	Wang, Ruyu, Hu, Qing, Wang, Haonan, Zhu, Guanghao, Wang, Mengge, Zhang, Qian, Zhao, Yishu, Li, Chunyu, Zhang, Yani, Ge, Guangbo, Chen, Hongzhuan, Chen, Lili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064871/ https://www.ncbi.nlm.nih.gov/pubmed/33901557 http://dx.doi.org/10.1016/j.ijbiomac.2021.04.129

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