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Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico cloning and immune simulation

Reports of the novel and more contagious strains of SARS-CoV-2 originating in different countries have further aggravated the pandemic situation. The recent substitutions in spike protein may be critical for the virus to evade the host's immune system and therapeutics that have already been dev...

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Detalles Bibliográficos
Autores principales: Khan, Abbas, Khan, Shahzeb, Saleem, Shoaib, Nizam-Uddin, N., Mohammad, Anwar, Khan, Taimoor, Ahmad, Sajjad, Arshad, Muhammad, Ali, Syed Shujait, Suleman, Muhammad, Wei, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064902/
https://www.ncbi.nlm.nih.gov/pubmed/33930764
http://dx.doi.org/10.1016/j.compbiomed.2021.104420