HIMF deletion ameliorates acute myocardial ischemic injury by promoting macrophage transformation to reparative subtype

Appropriately manipulating macrophage M1/M2 phenotypic transition is a promising therapeutic strategy for tissue repair after myocardial infarction (MI). Here we showed that gene ablation of hypoxia-induced mitogenic factor (HIMF) in mice (Himf(−/−) and HIMF(flox/flox);Lyz2-Cre) attenuated M1 macrop...

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Detalles Bibliográficos
Autores principales: Li, Yanjiao, Dong, Min, Wang, Qing, Kumar, Santosh, Zhang, Rui, Cheng, Wanwen, Xiang, Jiaqing, Wang, Gang, Ouyang, Kunfu, Zhou, Ruxing, Xie, Yaohong, Lu, Yishen, Yi, Jing, Duan, Haixia, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064941/
https://www.ncbi.nlm.nih.gov/pubmed/33893593
http://dx.doi.org/10.1007/s00395-021-00867-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064941/
https://www.ncbi.nlm.nih.gov/pubmed/33893593
http://dx.doi.org/10.1007/s00395-021-00867-7

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