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Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction

Upon activation, neutrophils release neutrophil extracellular traps (NETs), which contribute to circulating DNA burden and thrombosis, including ST-segment elevation myocardial infarction (STEMI). Deoxyribonuclease (DNase) 1 degrades circulating DNA and NETs. Lower DNase activity correlates with NET...

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Detalles Bibliográficos
Autores principales: Hofbauer, Thomas M., Mangold, Andreas, Ondracek, Anna S., Panzenböck, Adelheid, Scherz, Thomas, Müller, Julian, Distelmaier, Klaus, Seidl, Veronika, Kastl, Stefan, Müller-Nurasyid, Martina, Peters, Annette, Strauch, Konstantin, Winker, Robert, Wohlschläger-Krenn, Evelyne, Nistler, Sonja, Lang, Irene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064981/
https://www.ncbi.nlm.nih.gov/pubmed/33891165
http://dx.doi.org/10.1007/s00395-021-00864-w