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RANKL regulates male reproductive function

Infertile men have few treatment options. Here, we demonstrate that the transmembrane receptor activator of NF-kB ligand (RANKL) signaling system is active in mouse and human testis. RANKL is highly expressed in Sertoli cells and signals through RANK, expressed in most germ cells, whereas the RANKL-...

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Detalles Bibliográficos
Autores principales: Blomberg Jensen, Martin, Andreassen, Christine Hjorth, Jørgensen, Anne, Nielsen, John Erik, Juel Mortensen, Li, Boisen, Ida Marie, Schwarz, Peter, Toppari, Jorma, Baron, Roland, Lanske, Beate, Juul, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065035/
https://www.ncbi.nlm.nih.gov/pubmed/33893301
http://dx.doi.org/10.1038/s41467-021-22734-8