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Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance

Heterochromatin is a critical chromatin compartment, whose integrity governs genome stability and cell fate transitions. How heterochromatin features, including higher-order chromatin folding and histone modifications associated with transcriptional silencing, are maintained following a genotoxic st...

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Detalles Bibliográficos
Autores principales: Fortuny, Anna, Chansard, Audrey, Caron, Pierre, Chevallier, Odile, Leroy, Olivier, Renaud, Olivier, Polo, Sophie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065061/
https://www.ncbi.nlm.nih.gov/pubmed/33893291
http://dx.doi.org/10.1038/s41467-021-22575-5