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Imaging the response to DNA damage in heterochromatin domains reveals core principles of heterochromatin maintenance
Heterochromatin is a critical chromatin compartment, whose integrity governs genome stability and cell fate transitions. How heterochromatin features, including higher-order chromatin folding and histone modifications associated with transcriptional silencing, are maintained following a genotoxic st...
Autores principales: | Fortuny, Anna, Chansard, Audrey, Caron, Pierre, Chevallier, Odile, Leroy, Olivier, Renaud, Olivier, Polo, Sophie E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065061/ https://www.ncbi.nlm.nih.gov/pubmed/33893291 http://dx.doi.org/10.1038/s41467-021-22575-5 |
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