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Transgenic mice overexpressing the LH receptor in the female reproductive system spontaneously develop endometrial tumour masses

The receptor for the luteinizing hormone (LH-R) is aberrantly over expressed in cancers of the reproductive system. To uncover whether LH-R over expression has a causative role in cancer, we generated a transgenic (TG) mouse which overexpresses the human LH-R (hLH-R) in the female reproductive tract...

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Detalles Bibliográficos
Autores principales: Lottini, Tiziano, Iorio, Jessica, Lastraioli, Elena, Carraresi, Laura, Duranti, Claudia, Sala, Cesare, Armenio, Miriam, Noci, Ivo, Pillozzi, Serena, Arcangeli, Annarosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065064/
https://www.ncbi.nlm.nih.gov/pubmed/33893331
http://dx.doi.org/10.1038/s41598-021-87492-5