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Human biodistribution and dosimetry of [(11)C]-UCB-J, a PET radiotracer for imaging synaptic density

RATIONALE: [(11)C]-UCB-J is an emerging tool for the noninvasive measurement of synaptic vesicle density in vivo. Here, we report human biodistribution and dosimetry estimates derived from sequential whole-body PET using two versions of the OLINDA dosimetry program. METHODS: Sequential whole-body PE...

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Detalles Bibliográficos
Autores principales: Cawthorne, Christopher, Maguire, Paul, Mercier, Joel, Sciberras, David, Serdons, Kim, Bormans, Guy, de Hoon, Jan, Van Laere, Koen, Koole, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065069/
https://www.ncbi.nlm.nih.gov/pubmed/33891195
http://dx.doi.org/10.1186/s40658-021-00384-5