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The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell line

Microglia, resident macrophages of the brain that act as primary immune cells, play essential roles in innate immunity and neuroinflammatory pathologies. Microglial cells are rapidly activated in response to infection and inflammation/injury, associated with the expression of proinflammatory genes a...

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Detalles Bibliográficos
Autores principales: Baek, Mina, Yoo, Eunyoung, Choi, Hae In, An, Ga Yeong, Chai, Jin Choul, Lee, Young Seek, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065145/
https://www.ncbi.nlm.nih.gov/pubmed/33893325
http://dx.doi.org/10.1038/s41598-021-87828-1