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The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell line
Microglia, resident macrophages of the brain that act as primary immune cells, play essential roles in innate immunity and neuroinflammatory pathologies. Microglial cells are rapidly activated in response to infection and inflammation/injury, associated with the expression of proinflammatory genes a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065145/ https://www.ncbi.nlm.nih.gov/pubmed/33893325 http://dx.doi.org/10.1038/s41598-021-87828-1 |