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Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors

Age-related macular degeneration and other macular diseases result in the loss of light-sensing cone photoreceptors, causing irreversible sight impairment. Photoreceptor replacement may restore vision by transplanting healthy cells, which must form new synaptic connections with the recipient retina....

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Detalles Bibliográficos
Autores principales: Ribeiro, Joana, Procyk, Christopher A., West, Emma L., O’Hara-Wright, Michelle, Martins, Monica F., Khorasani, Majid Moshtagh, Hare, Aura, Basche, Mark, Fernando, Milan, Goh, Debbie, Jumbo, Neeraj, Rizzi, Matteo, Powell, Kate, Tariq, Menahil, Michaelides, Michel, Bainbridge, James W.B., Smith, Alexander J., Pearson, Rachael A., Gonzalez-Cordero, Anai, Ali, Robin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065177/
https://www.ncbi.nlm.nih.gov/pubmed/33882303
http://dx.doi.org/10.1016/j.celrep.2021.109022