Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo?

BACKGROUND: Diabetes always involves variable degrees of β-cell demise and malfunction leading to insufficient insulin secretion. Besides clinical investigations, many research projects used rodent islets to study various facets of β-cell pathophysiology. Their important contributions laid the found...

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Detalles Bibliográficos
Autor principal: Henquin, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065218/
https://www.ncbi.nlm.nih.gov/pubmed/33737253
http://dx.doi.org/10.1016/j.molmet.2021.101212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065218/
https://www.ncbi.nlm.nih.gov/pubmed/33737253
http://dx.doi.org/10.1016/j.molmet.2021.101212

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