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Oxygen-independent disulfide bond formation in VEGF-A and CA9

Low levels of oxygen (hypoxia) occurs in many (patho)physiological situations. Adaptation to hypoxia is in part mediated by proteins expressed in the extracellular space that mature in the endoplasmic reticulum (ER) prior to traversing the secretory pathway. The majority of such ER cargo proteins re...

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Detalles Bibliográficos
Autores principales: Levitin, Fiana, Lee, Sandy Che-Eun S., Hulme, Stephanie, Rumantir, Ryan A., Wong, Amy S., Meester, Marmendia R., Koritzinsky, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065220/
https://www.ncbi.nlm.nih.gov/pubmed/33675747
http://dx.doi.org/10.1016/j.jbc.2021.100505