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Recent advances in de novo protein design: Principles, methods, and applications

The computational de novo protein design is increasingly applied to address a number of key challenges in biomedicine and biological engineering. Successes in expanding applications are driven by advances in design principles and methods over several decades. Here, we review recent innovations in ma...

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Detalles Bibliográficos
Autores principales: Pan, Xingjie, Kortemme, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065224/
https://www.ncbi.nlm.nih.gov/pubmed/33744284
http://dx.doi.org/10.1016/j.jbc.2021.100558