Novel Mechanism for Memantine in Attenuating Diabetic Neuropathic Pain in Mice via Downregulating the Spinal HMGB1/TRL4/NF-kB Inflammatory Axis

Diabetic neuropathic pain (DNP) is a common diabetic complication that currently lacks an efficient therapy. The aim of the current work was to uncover the anti-allodynic and neuroprotective effects of memantine in a model of mouse diabetic neuropathy and its ameliorative effect on the high-mobility...

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Detalles Bibliográficos
Autores principales: Alomar, Suliman Y., Gheit, Rehab E. Abo El, Enan, Eman T., El-Bayoumi, Khaled S., Shoaeir, Mohamed Z., Elkazaz, Amany Y., Al Thagfan, Sultan S., Zaitone, Sawsan A., El-Sayed, Rehab M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065430/
https://www.ncbi.nlm.nih.gov/pubmed/33915770
http://dx.doi.org/10.3390/ph14040307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065430/
https://www.ncbi.nlm.nih.gov/pubmed/33915770
http://dx.doi.org/10.3390/ph14040307

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