Cargando…
Novel Mechanism for Memantine in Attenuating Diabetic Neuropathic Pain in Mice via Downregulating the Spinal HMGB1/TRL4/NF-kB Inflammatory Axis
Diabetic neuropathic pain (DNP) is a common diabetic complication that currently lacks an efficient therapy. The aim of the current work was to uncover the anti-allodynic and neuroprotective effects of memantine in a model of mouse diabetic neuropathy and its ameliorative effect on the high-mobility...
Autores principales: | Alomar, Suliman Y., Gheit, Rehab E. Abo El, Enan, Eman T., El-Bayoumi, Khaled S., Shoaeir, Mohamed Z., Elkazaz, Amany Y., Al Thagfan, Sultan S., Zaitone, Sawsan A., El-Sayed, Rehab M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065430/ https://www.ncbi.nlm.nih.gov/pubmed/33915770 http://dx.doi.org/10.3390/ph14040307 |
Ejemplares similares
-
Carbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation
por: Elsherbiny, Nehal M., et al.
Publicado: (2019) -
Formulation and Characterization of Doxycycline-Loaded Polymeric Nanoparticles for Testing Antitumor/Antiangiogenic Action in Experimental Colon Cancer in Mice
por: Alshaman, Reem, et al.
Publicado: (2022) -
Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis
por: Gheit, Rehab E. Abo El, et al.
Publicado: (2022) -
Correction: Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis
por: Gheit, Rehab E. Abo El, et al.
Publicado: (2023) -
Metformin Protects From Rotenone–Induced Nigrostriatal Neuronal Death in Adult Mice by Activating AMPK-FOXO3 Signaling and Mitigation of Angiogenesis
por: El-Ghaiesh, Sabah H., et al.
Publicado: (2020)