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Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3

A new hypothesis highlights sleep-dependent learning/memory consolidation and regards the sleep-wake cycle as a modulator of β-amyloid and tau Alzheimer’s disease (AD) pathologies. Sundowning behavior is a common neuropsychiatric symptom (NPS) associated with dementia. Sleep fragmentation resulting...

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Detalles Bibliográficos
Autores principales: Giménez-Llort, Lydia, Santana-Santana, Mikel, Ratia, Míriam, Pérez, Belén, Camps, Pelayo, Muñoz-Torrero, Diego, Badia, Albert, Clos, Maria Victòria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065516/
https://www.ncbi.nlm.nih.gov/pubmed/33810622
http://dx.doi.org/10.3390/brainsci11040426