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The Role of Nuclear Insulin and IGF1 Receptors in Metabolism and Cancer

Insulin (InsR) and insulin-like growth factor-1 (IGF1R) receptors mediate the metabolic and growth-promoting actions of insulin and IGF1/IGF2, respectively. Evidence accumulated in recent years indicates that, in addition to their typical cell-surface localization pattern and ligand-activated mechan...

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Detalles Bibliográficos
Autores principales: Werner, Haim, Sarfstein, Rive, Laron, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065599/
https://www.ncbi.nlm.nih.gov/pubmed/33918477
http://dx.doi.org/10.3390/biom11040531