Targeting Pin1 for Modulation of Cell Motility and Cancer Therapy

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) specifically binds and isomerizes the phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif, which leads to changes in protein conformation and function. Pin1 is widely overexpressed in cancers and plays an important role in tumori...

Descripción completa

Detalles Bibliográficos
Autores principales: Chuang, Hsiang-Hao, Zhen, Yen-Yi, Tsai, Yu-Chen, Chuang, Cheng-Hao, Huang, Ming-Shyan, Hsiao, Michael, Yang, Chih-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065645/
https://www.ncbi.nlm.nih.gov/pubmed/33807199
http://dx.doi.org/10.3390/biomedicines9040359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065645/
https://www.ncbi.nlm.nih.gov/pubmed/33807199
http://dx.doi.org/10.3390/biomedicines9040359

Ejemplares similares