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Targeting Pin1 for Modulation of Cell Motility and Cancer Therapy

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) specifically binds and isomerizes the phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif, which leads to changes in protein conformation and function. Pin1 is widely overexpressed in cancers and plays an important role in tumori...

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Detalles Bibliográficos
Autores principales:	Chuang, Hsiang-Hao, Zhen, Yen-Yi, Tsai, Yu-Chen, Chuang, Cheng-Hao, Huang, Ming-Shyan, Hsiao, Michael, Yang, Chih-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065645/ https://www.ncbi.nlm.nih.gov/pubmed/33807199 http://dx.doi.org/10.3390/biomedicines9040359

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