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High Dietary Phosphate Exacerbates and Acts Independently of Low Autophagy Activity in Pathological Cardiac Remodeling and Dysfunction

High phosphate contributes to uremic cardiomyopathy. Abnormal autophagy is associated with the development and progression of heart disease. What is unknown is the effects of phosphate on autophagy and whether the ill effects of phosphate on cardiomyocytes are mediated by low autophagy. High (2.0% w...

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Detalles Bibliográficos
Autores principales: Shi, Mingjun, Shepard, Sierra, Zhou, Zhiyong, Maique, Jenny, Seli, Olivia, Moe, Orson W., Hu, Ming Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065663/
https://www.ncbi.nlm.nih.gov/pubmed/33915953
http://dx.doi.org/10.3390/cells10040777