Eltrombopag Improves Erythroid Differentiation in a Human Induced Pluripotent Stem Cell Model of Diamond Blackfan Anemia

Diamond Blackfan Anemia (DBA) is a congenital macrocytic anemia associated with ribosomal protein haploinsufficiency. Ribosomal dysfunction delays globin synthesis, resulting in excess toxic free heme in erythroid progenitors, early differentiation arrest, and pure red cell aplasia. In this study, D...

Descripción completa

Detalles Bibliográficos
Autores principales: Qanash, Husam, Li, Yongqin, Smith, Richard H., Linask, Kaari, Young-Baird, Sara, Hakami, Waleed, Keyvanfar, Keyvan, Choy, John S., Zou, Jizhong, Larochelle, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065708/
https://www.ncbi.nlm.nih.gov/pubmed/33810313
http://dx.doi.org/10.3390/cells10040734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065708/
https://www.ncbi.nlm.nih.gov/pubmed/33810313
http://dx.doi.org/10.3390/cells10040734

Ejemplares similares