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Shikonin Derivatives from Onsoma visianii Decrease Expression of Phosphorylated STAT3 in Leukemia Cells and Exert Antitumor Activity

Antitumor effects of shikonins on chronic lymphocytic leukemia (CLL) and B-cell prolymphocytic leukemia (B-PLL) are mostly unexplored. The antitumor activity of shikonins, isolated from Onosma visianii Clem (Boraginaceae), in BCL1, mouse CLL cells and JVM-13, human B-PLL cells was explored in this s...

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Detalles Bibliográficos
Autores principales: Todorovic, Zeljko, Milovanovic, Jelena, Arsenijevic, Dragana, Vukovic, Nenad, Vukic, Milena, Arsenijevic, Aleksandar, Djurdjevic, Predrag, Milovanovic, Marija, Arsenijevic, Nebojsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065735/
https://www.ncbi.nlm.nih.gov/pubmed/33807148
http://dx.doi.org/10.3390/nu13041147