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Pharmacological Inhibition of S-Nitrosoglutathione Reductase Reduces Cardiac Damage Induced by Ischemia–Reperfusion

The cardioprotective effects of nitric oxide (NO) have been described through S-nitrosylation of several important proteins in the mitochondria of the cardiomyocyte. S-nitrosoglutathione reductase (GSNOR) is an enzyme involved in the metabolism of S-nitrosothiols by producing denitrosylation, thus l...

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Detalles Bibliográficos
Autores principales: Castillo, Oscar Arriagada, Herrera, Gustavo, Manriquez, Carlos, Rojas, Andrea F., González, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065739/
https://www.ncbi.nlm.nih.gov/pubmed/33918310
http://dx.doi.org/10.3390/antiox10040555