Hypertrophy-Reduced Autophagy Causes Cardiac Dysfunction by Directly Impacting Cardiomyocyte Contractility

Cardiac remodeling and contractile dysfunction are leading causes in hypertrophy-associated heart failure (HF), increasing with a population’s rising age. A hallmark of aged and diseased hearts is the accumulation of modified proteins caused by an impaired autophagy-lysosomal-pathway. Although, auto...

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Detalles Bibliográficos
Autores principales: Ott, Christiane, Jung, Tobias, Brix, Sarah, John, Cathleen, Betz, Iris R., Foryst-Ludwig, Anna, Deubel, Stefanie, Kuebler, Wolfgang M., Grune, Tilman, Kintscher, Ulrich, Grune, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065800/
https://www.ncbi.nlm.nih.gov/pubmed/33916597
http://dx.doi.org/10.3390/cells10040805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065800/
https://www.ncbi.nlm.nih.gov/pubmed/33916597
http://dx.doi.org/10.3390/cells10040805

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