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Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells

Triple negative breast cancer (TNBC) is associated with unfavorable prognosis and high relapse rates following chemotherapy. There is an urgent need to develop effective targeted therapy for this BC subtype. The type I insulin-like growth factor receptor (IGF-IR) was identified as a potential target...

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Detalles Bibliográficos
Autores principales: Tsui, Jennifer, Qi, Shu, Perrino, Stephanie, Leibovitch, Matthew, Brodt, Pnina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065809/
https://www.ncbi.nlm.nih.gov/pubmed/33916323
http://dx.doi.org/10.3390/biom11040527