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Saccharomyces cerevisiae as a Toolkit for COP9 Signalosome Research

The COP9 signalosome (CSN) is a highly conserved eukaryotic multi-subunit enzyme, regulating cullin RING ligase activities and accordingly, substrate ubiquitination and degradation. We showed that the CSN complex of Saccharomyces cerevisiae that is deviated in subunit composition and in sequence hom...

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Detalles Bibliográficos
Autores principales: Harshuk-Shabso, Dana, Castel, Noam, Israeli, Ran, Harari, Sheri, Pick, Elah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065851/
https://www.ncbi.nlm.nih.gov/pubmed/33806190
http://dx.doi.org/10.3390/biom11040497