High Glucose Treatment Limits Drosha Protein Expression and Alters AngiomiR Maturation in Microvascular Primary Endothelial Cells via an Mdm2-dependent Mechanism

Diabetes promotes an angiostatic phenotype in the microvascular endothelium of skeletal muscle and skin. Angiogenesis-related microRNAs (angiomiRs) regulate angiogenesis through the translational repression of pro- and anti-angiogenic genes. The maturation of micro-RNA (miRs), including angiomiRs, r...

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Detalles Bibliográficos
Autores principales: Lam, Brian, Nwadozi, Emmanuel, Haas, Tara L., Birot, Olivier, Roudier, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065922/
https://www.ncbi.nlm.nih.gov/pubmed/33801773
http://dx.doi.org/10.3390/cells10040742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065922/
https://www.ncbi.nlm.nih.gov/pubmed/33801773
http://dx.doi.org/10.3390/cells10040742

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