Evaluation of Vertebrate-Specific Replication-Defective Zika Virus, a Novel Single-Cycle Arbovirus Vaccine, in a Mouse Model

The flavivirus Zika (ZIKV) has emerged as a global threat, making the development of a ZIKV vaccine a priority. While live-attenuated vaccines are known to induce long-term immunity but reduced safety, inactivated vaccines exhibit a weaker immune response as a trade-off for increased safety margins....

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Detalles Bibliográficos
Autores principales: Wan, Shengfeng, Cao, Shengbo, Wang, Xugang, Zhou, Yanfei, Yan, Weidong, Gu, Xinbin, Wu, Tzyy-Choou, Pang, Xiaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065927/
https://www.ncbi.nlm.nih.gov/pubmed/33916109
http://dx.doi.org/10.3390/vaccines9040338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065927/
https://www.ncbi.nlm.nih.gov/pubmed/33916109
http://dx.doi.org/10.3390/vaccines9040338

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