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Green Nanotechnology in the Formulation of a Novel Solid Dispersed Multilayered Core-Sheath Raloxifene-Loaded Nanofibrous Buccal Film; In Vitro and In Vivo Characterization

Green nanotechnology utilizes the principles of green chemistry to formulate eco-friendly nanocarrier systems to mitigate patients and environment hazards. Raloxifene (RLX) demonstrates poor aqueous solubility (BCS class II) and low bioavailability, only 2% (extensive first-pass metabolism). The aim...

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Detalles Bibliográficos
Autores principales: Nageeb El-Helaly, Sara, Abd-Elrasheed, Eman, Salim, Samar A., Fahmy, Rania H., Salah, Salwa, EL-Ashmoony, Manal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066100/
https://www.ncbi.nlm.nih.gov/pubmed/33915828
http://dx.doi.org/10.3390/pharmaceutics13040474