Metabolic Profiles of New Unsymmetrical Bisacridine Antitumor Agents in Electrochemical and Enzymatic Noncellular Systems and in Tumor Cells

New unsymmetrical bisacridines (UAs) demonstrated high activity not only against a set of tumor cell lines but also against human tumor xenografts in nude mice. Representative UA compounds, named C-2028, C-2045 and C-2053, were characterized in respect to their physicochemical properties and the fol...

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Detalles Bibliográficos
Autores principales: Mieszkowska, Anna, Nowicka, Anna M., Kowalczyk, Agata, Potęga, Agnieszka, Pawłowska, Monika, Kosno, Michał, Augustin, Ewa, Mazerska, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066102/
https://www.ncbi.nlm.nih.gov/pubmed/33915981
http://dx.doi.org/10.3390/ph14040317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066102/
https://www.ncbi.nlm.nih.gov/pubmed/33915981
http://dx.doi.org/10.3390/ph14040317

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