Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration

Age-related macular degeneration (AMD), the leading cause of vision loss in the elderly, is characterized by loss of the retinal pigment epithelium (RPE). While the disease mechanism remains unclear, prior studies have linked AMD with RPE mitochondrial defects and genetic polymorphisms in the comple...

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Detalles Bibliográficos
Autores principales: Ebeling, Mara C., Geng, Zhaohui, Kapphahn, Rebecca J., Roehrich, Heidi, Montezuma, Sandra R., Dutton, James R., Ferrington, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066149/
https://www.ncbi.nlm.nih.gov/pubmed/33918210
http://dx.doi.org/10.3390/cells10040789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066149/
https://www.ncbi.nlm.nih.gov/pubmed/33918210
http://dx.doi.org/10.3390/cells10040789

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