Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound

Autophagic cell death (ACD) is an alternative death mechanism in resistant malignant cancer cells. In this study, we demonstrated how polyphenol stilbene compound PE5 exhibits potent ACD-promoting activity in lung cancer cells that may offer an opportunity for novel cancer treatment. Cell death caus...

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Detalles Bibliográficos
Autores principales: Tungsukruthai, Sucharat, Reamtong, Onrapak, Roytrakul, Sittiruk, Sukrong, Suchada, Vinayanwattikun, Chanida, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066183/
https://www.ncbi.nlm.nih.gov/pubmed/33805467
http://dx.doi.org/10.3390/antiox10040534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066183/
https://www.ncbi.nlm.nih.gov/pubmed/33805467
http://dx.doi.org/10.3390/antiox10040534

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