Cargando…

Targeting Dietary and Microbial Tryptophan-Indole Metabolism as Therapeutic Approaches to Colon Cancer

Tryptophan metabolism, via the kynurenine (Kyn) pathway, and microbial transformation of tryptophan to indolic compounds are fundamental for host health; both of which are altered in colon carcinogenesis. Alterations in tryptophan metabolism begin early in colon carcinogenesis as an adaptive mechani...

Descripción completa

Detalles Bibliográficos
Autores principales: Wyatt, Madhur, Greathouse, K. Leigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066279/
https://www.ncbi.nlm.nih.gov/pubmed/33916690
http://dx.doi.org/10.3390/nu13041189