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Parkinson’s Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, characterized by progressive loss of dopaminergic neurons in the substantia nigra, intraneuronal deposition of misfolded proteins known as Lewy bodies, and chronic neuroinflammation. PD can arise from monogenic mutation...

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Detalles Bibliográficos
Autores principales: Ding, Yingzhuo, Li, Yan, Chhetri, Gaurav, Peng, Xiaoxin, Wu, Jing, Wang, Zejian, Zhao, Bo, Zhao, Wenjuan, Li, Xueyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066283/
https://www.ncbi.nlm.nih.gov/pubmed/33800686
http://dx.doi.org/10.3390/cells10040746