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Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged

Since its discovery, evidence that siRNA was able to act as an RNA interference effector, led to its acceptation as a novel medicine. The siRNA approach is very effective, due to its catalytic mechanism, but still the limitations of its cellular delivery should be addressed. One promising form of no...

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Detalles Bibliográficos
Autores principales: Ahmed, Shayan, Salmon, Hugo, Distasio, Nicholas, Do, Hai Doan, Scherman, Daniel, Alhareth, Khair, Tabrizian, Maryam, Mignet, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066317/
https://www.ncbi.nlm.nih.gov/pubmed/33916066
http://dx.doi.org/10.3390/pharmaceutics13040479