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Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged
Since its discovery, evidence that siRNA was able to act as an RNA interference effector, led to its acceptation as a novel medicine. The siRNA approach is very effective, due to its catalytic mechanism, but still the limitations of its cellular delivery should be addressed. One promising form of no...
Autores principales: | Ahmed, Shayan, Salmon, Hugo, Distasio, Nicholas, Do, Hai Doan, Scherman, Daniel, Alhareth, Khair, Tabrizian, Maryam, Mignet, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066317/ https://www.ncbi.nlm.nih.gov/pubmed/33916066 http://dx.doi.org/10.3390/pharmaceutics13040479 |
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