Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)

Oligonucleotides (OND) represent a promising therapeutic approach. However, their instability and low intestinal permeability hamper oral bioavailability. Well-established for oral delivery, self-emulsifying drug delivery systems (SEDDS) can overcome the weakness of other delivery systems such as lo...

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Detalles Bibliográficos
Autores principales: Kubackova, Jana, Holas, Ondrej, Zbytovska, Jarmila, Vranikova, Barbora, Zeng, Guanghong, Pavek, Petr, Mullertz, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066367/
https://www.ncbi.nlm.nih.gov/pubmed/33800701
http://dx.doi.org/10.3390/pharmaceutics13040459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066367/
https://www.ncbi.nlm.nih.gov/pubmed/33800701
http://dx.doi.org/10.3390/pharmaceutics13040459

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