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Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)
Oligonucleotides (OND) represent a promising therapeutic approach. However, their instability and low intestinal permeability hamper oral bioavailability. Well-established for oral delivery, self-emulsifying drug delivery systems (SEDDS) can overcome the weakness of other delivery systems such as lo...
Autores principales: | Kubackova, Jana, Holas, Ondrej, Zbytovska, Jarmila, Vranikova, Barbora, Zeng, Guanghong, Pavek, Petr, Mullertz, Anette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066367/ https://www.ncbi.nlm.nih.gov/pubmed/33800701 http://dx.doi.org/10.3390/pharmaceutics13040459 |
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