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Recent Trends in Synthesis of Chloramphenicol New Derivatives

Chloramphenicol (CAM), the bacteriostatic broad-spectrum antibiotic, isolated from Streptomyces venezuelae during the “golden era” of antibiotic discovery, nowadays has limited clinical potential due to adverse side effects and frequent antimicrobial resistance. Numerous CAM analogs were synthesized...

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Detalles Bibliográficos
Autor principal: Tevyashova, Anna N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066525/
https://www.ncbi.nlm.nih.gov/pubmed/33807439
http://dx.doi.org/10.3390/antibiotics10040370