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A Placebo-Controlled, Double-Blind Randomized (Phase IIB) Trial of Oral Administration with HPV16 E7-Expressing Lactobacillus, GLBL101c, for the Treatment of Cervical Intraepithelial Neoplasia Grade 2 (CIN2)

Cervical intraepithelial neoplasia (CIN), a precursor lesion to cervical cancer, is caused by high-risk human papillomavirus (HPV); high-grade CIN lesions (CIN2-3) are precancerous and require treatment. No globally approved therapy is available for CIN2-3 treatment. This study is a placebo-controll...

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Detalles Bibliográficos
Autores principales: Ikeda, Yuji, Adachi, Katsuyuki, Tomio, Kensuke, Eguchi-Kojima, Satoko, Tsuruga, Tetsushi, Uchino-Mori, Mayuyo, Taguchi, Ayumi, Komatsu, Atsushi, Nagamatsu, Takeshi, Oda, Katsutoshi, Kawana-Tachikawa, Ai, Uemura, Yukari, Igimi, Shizunobu, Osuga, Yutaka, Fujii, Tomoyuki, Kawana, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066592/
https://www.ncbi.nlm.nih.gov/pubmed/33915901
http://dx.doi.org/10.3390/vaccines9040329