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A Placebo-Controlled, Double-Blind Randomized (Phase IIB) Trial of Oral Administration with HPV16 E7-Expressing Lactobacillus, GLBL101c, for the Treatment of Cervical Intraepithelial Neoplasia Grade 2 (CIN2)
Cervical intraepithelial neoplasia (CIN), a precursor lesion to cervical cancer, is caused by high-risk human papillomavirus (HPV); high-grade CIN lesions (CIN2-3) are precancerous and require treatment. No globally approved therapy is available for CIN2-3 treatment. This study is a placebo-controll...
Autores principales: | Ikeda, Yuji, Adachi, Katsuyuki, Tomio, Kensuke, Eguchi-Kojima, Satoko, Tsuruga, Tetsushi, Uchino-Mori, Mayuyo, Taguchi, Ayumi, Komatsu, Atsushi, Nagamatsu, Takeshi, Oda, Katsutoshi, Kawana-Tachikawa, Ai, Uemura, Yukari, Igimi, Shizunobu, Osuga, Yutaka, Fujii, Tomoyuki, Kawana, Kei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066592/ https://www.ncbi.nlm.nih.gov/pubmed/33915901 http://dx.doi.org/10.3390/vaccines9040329 |
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