Omega-3 Fatty Acids Upregulate SIRT1/3, Activate PGC-1α via Deacetylation, and Induce Nrf1 Production in 5/6 Nephrectomy Rat Model

Mitochondrial dysfunction contributes to the pathogenesis of kidney injury related with cardiovascular disease. Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) protects renal tubular cells by upregulating nuclear factor erythroid 2-related factor 2 (Nrf2). AMP-activated...

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Detalles Bibliográficos
Autores principales: Son, Sung Hyun, Lee, Su Mi, Lee, Mi Hwa, Son, Young Ki, Kim, Seong Eun, An, Won Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066610/
https://www.ncbi.nlm.nih.gov/pubmed/33810216
http://dx.doi.org/10.3390/md19040182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066610/
https://www.ncbi.nlm.nih.gov/pubmed/33810216
http://dx.doi.org/10.3390/md19040182

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