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NHS-Functionalized THP Derivative for Efficient Synthesis of Kit-Based Precursors for (68)Ga Labeled PET Probes

Hexadentate tris(3,4-hydroxypyridinone) ligands (THP) complex Fe(3+) at very low iron concentrations and their high affinities for oxophilic trivalent metal ions have led to their development for new applications as bifunctional chelators for the radiometal gallium-68 ((68)Ga). THP-peptide bioconjug...

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Detalles Bibliográficos
Autores principales: Floresta, Giuseppe, Keeling, George P., Memdouh, Siham, Meszaros, Levente K., de Rosales, Rafael T. M., Abbate, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066796/
https://www.ncbi.nlm.nih.gov/pubmed/33915871
http://dx.doi.org/10.3390/biomedicines9040367