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Inhibition of Cochlear HMGB1 Expression Attenuates Oxidative Stress and Inflammation in an Experimental Murine Model of Noise-Induced Hearing Loss

Noise-induced hearing loss (NIHL) is a common inner ear disease but has complex pathological mechanisms, one of which is increased oxidative stress in the cochlea. The high-mobility group box 1 (HMGB1) protein acts as an inflammatory mediator and shows different activities with redox modifications l...

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Detalles Bibliográficos
Autores principales: Shih, Cheng-Ping, Kuo, Chao-Yin, Lin, Yuan-Yung, Lin, Yi-Chun, Chen, Hang-Kang, Wang, Hao, Chen, Hsin-Chien, Wang, Chih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066810/
https://www.ncbi.nlm.nih.gov/pubmed/33916471
http://dx.doi.org/10.3390/cells10040810