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Inhibition of Cochlear HMGB1 Expression Attenuates Oxidative Stress and Inflammation in an Experimental Murine Model of Noise-Induced Hearing Loss
Noise-induced hearing loss (NIHL) is a common inner ear disease but has complex pathological mechanisms, one of which is increased oxidative stress in the cochlea. The high-mobility group box 1 (HMGB1) protein acts as an inflammatory mediator and shows different activities with redox modifications l...
Autores principales: | Shih, Cheng-Ping, Kuo, Chao-Yin, Lin, Yuan-Yung, Lin, Yi-Chun, Chen, Hang-Kang, Wang, Hao, Chen, Hsin-Chien, Wang, Chih-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066810/ https://www.ncbi.nlm.nih.gov/pubmed/33916471 http://dx.doi.org/10.3390/cells10040810 |
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