Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes

BACKGROUND: Genetic variants in the human leukocyte antigen (HLA) locus contribute to the risk for developing scleroderma/systemic sclerosis (SSc). However, there are other replicated loci that also contribute to genetic risk for SSc, and it is unknown whether genetic risk in these non-HLA loci acts...

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Detalles Bibliográficos
Autores principales: Poppenberg, Kerry E., Tutino, Vincent M., Tarbell, Evan, Jarvis, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066847/
https://www.ncbi.nlm.nih.gov/pubmed/33894768
http://dx.doi.org/10.1186/s12920-021-00964-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066847/
https://www.ncbi.nlm.nih.gov/pubmed/33894768
http://dx.doi.org/10.1186/s12920-021-00964-5

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