Refinement of Animal Model of Colorectal Carcinogenesis through the Definition of Novel Humane Endpoints

SIMPLE SUMMARY: Ensuring animal welfare is essential in protocols using laboratory animals. Applying a score sheet with 14 biological parameters, we assessed the welfare of 29 male Wistar rats used as models of colorectal carcinogenesis (CRC). We found a uniformity of characteristics preceding the p...

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Detalles Bibliográficos
Autores principales: Silva-Reis, Rita, Faustino-Rocha, Ana I., Gonçalves, Mariana, Ribeiro, Catarina Castro, Ferreira, Tiago, Ribeiro-Silva, Carla, Gonçalves, Lio, Antunes, Luís, Venâncio, Carlos, Ferreira, Rita, Gama, Adelina, Oliveira, Paula A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066901/
https://www.ncbi.nlm.nih.gov/pubmed/33915847
http://dx.doi.org/10.3390/ani11040985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066901/
https://www.ncbi.nlm.nih.gov/pubmed/33915847
http://dx.doi.org/10.3390/ani11040985

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