Impaired F(1)F(o)-ATP-Synthase Dimerization Leads to the Induction of Cyclophilin D-Mediated Autophagy-Dependent Cell Death and Accelerated Aging

Mitochondrial F(1)F(o)-ATP-synthase dimers play a critical role in shaping and maintenance of mitochondrial ultrastructure. Previous studies have revealed that ablation of the F(1)F(o)-ATP-synthase assembly factor PaATPE of the ascomycete Podospora anserina strongly affects cristae formation, increa...

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Detalles Bibliográficos
Autores principales: Warnsmann, Verena, Marschall, Lisa-Marie, Osiewacz, Heinz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066942/
https://www.ncbi.nlm.nih.gov/pubmed/33808173
http://dx.doi.org/10.3390/cells10040757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066942/
https://www.ncbi.nlm.nih.gov/pubmed/33808173
http://dx.doi.org/10.3390/cells10040757

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